Measures of the Efficiency of Natural Selection During Gene Substitution

Publication date: Available online 15 May 2019Source: Journal of Theoretical BiologyAuthor(s): H. Allen OrrAbstractNatural selection is not perfectly efficient: it does not cause the instantaneous substitution of a beneficial mutation. Instead, substitution takes time, reflecting the statistical consequences of fitness differences over some number of generations. In this note, I suggest two measures of the efficiency of natural selection during gene substitution. I compare these measures against both ideal (instantaneous) and failed evolution. I also compare these measures to Haldane's cost of natural selection.

Source: Journal of Theoretical Biology - May 16, 2019 Category: Biology Source Type: research