Large local reactions to Hymenoptera stings: outcome of re-stings in real-life - Bil ò MB, Martini M, Pravettoni V, Bignardi D, Bonadonna P, Cortellini G, Kosinska M, Macchia D, Mauro M, Meucci E, Nittner-Marszalska M, Patella V, Pio R, Quercia O, Reccardini F, Ridolo E, Rudenko M, Severino M.

BACKGROUND: Large local reaction to Hymenoptera stings is usually defined as a swelling>10 cm which lasts longer than 24h, sometimes associated with erythema, pruritus, and blisters. Currently, the risk of subsequent systemic reactions after re-stings is ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Related Links:

Sterile inflammation arises without external cause, such as infection or injury, and chronic sterile inflammation is a characteristic of aging. Inflammatory signaling becomes constant and pronounced in tissues, and the immune system is constantly roused to action. Processes, such as regeneration from injury, that depend upon a clear cycle of inflammation that starts, progresses, and resolves are significantly disrupted. It is no exaggeration to say that the downstream consequences of chronic inflammation accelerate the progression of all of the common age-related conditions. It is of great importance in atherosclerosis and...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Insect bites can be significantly cut using a cunning disguise, researchers findPainting a cow to look something like a zebra has been found to reduce fly bites by 50%.Researchers believe painting stripes on to cattle is a world-first and could become an environmentally friendly alternative to pesticides.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Animals Agriculture Science Australia news Japan CSIRO Insects Farming Animal welfare Environment World news Pesticides Source Type: news
ConclusionThe clinical history is essential for the allergological workup and therapeutic decision on Hymenoptera venom allergies. A short latency time and the absence of skin symptoms are indicators for severe systemic sting reactions, followed by the patient ’s age and baseline serum tryptase levels.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
Authors: Bilò MB, Tontini C, Martini M, Corsi A, Agolini S, Antonicelli L Abstract Summary: Hymenoptera venom allergy (HVA) is the most frequent cause of anaphylaxis in Europe, accounting for most of the severe reactions occurring in adults, and being the second cause of anaphylaxis in children. Prevention of further episodes in patients who developed a systemic reaction (SR) is based on the correct management of the allergic emergency, the referral to an allergist for a correct diagnosis, prescription of adrenaline auto-injectors (AAI) and specific venom immunotherapy (VIT), if recommended. Diagnosis is bas...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
We describe a patient with a genetic condition that results in an increased IFN state, stimulator of IFN genes (STING)-associated vasculopathy with onset in infancy (SAVI), who developed collapsing glomerulopathy during a flare of his disease. The patient was found to have APOL1 G1 and G2 risk variants. This case supports the role of IFN in inducing APOL1-associated collapsing glomerulopathy.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Checkpoint blockade antibodies have been approved as immunotherapy for multiple types of cancer, but the response rate and efficacy are still limited. There are few immunogenic cell death–inducing (ICD-inducing) drugs available that can kill cancer cells, enhance tumor immunogenicity, increase in vivo immune infiltration, and thereby boost a tumor response to immunotherapy. So far, the ICD markers have been identified as the few immunostimulating characteristics of dead cells, but whether the presence of such ICD markers on tumor cells translates into enhanced antitumor immunity in vivo is still being investigated. T...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
This article examines domestic counterterrorism sting operations in the USA. It considers why critics consider these operations unethical and illegitimate. In particular, it looks at claims that counterterrorism sting operations have entrapped innocent peo...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
Publication date: Available online 2 October 2019Source: Fish &Shellfish ImmunologyAuthor(s): Xiaofeng Jiang, Guangping Liu, Zhiyi Hu, Guiqian Chen, Jianqing Chen, Zhengbing LvAbstractThe leading cause of mortality due to colorectal cancer (CRC) is highly associated with the development of liver metastases. Recently, we described cGAMP that is closely related to the metastatic state wherein the progress of metastatic tumors is associated with favorable outcomes in a zebrafish xenograft model. cGAMP was administered and the expression levels of type-I interferons were induced amongst tumor tissues to illuminate the over...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: 1 October 2019Source: Cell Reports, Volume 29, Issue 1Author(s): Nobuhiro Tsuchiya, Rong Zhang, Tatsuaki Iwama, Norihiro Ueda, Tianyi Liu, Minako Tatsumi, Yutaka Sasaki, Ranmaru Shimoda, Yuki Osako, Yu Sawada, Yosuke Kubo, Azusa Miyashita, Satoshi Fukushima, Zhao Cheng, Ryo Nakaki, Keiyo Takubo, Seiji Okada, Shin Kaneko, Hironobu Ihn, Tsuneyasu KaishoSummaryType I interferons (IFNs) play important roles in antitumor immunity. We generated IFN-α-producing cells by genetically engineered induced pluripotent stem cell (iPSC)-derived proliferating myeloid cells (iPSC-pMCs). Local administration of IFN-&...
Source: Cell Reports - Category: Cytology Source Type: research
BACKGROUND: More than 1500 scorpion species exist worldwide, with a few scorpion species potentially lethal to humans. About 1 million stings annually result in>3000 deaths, but the incidence and mortality vary greatly by species and location. Physicians ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Non-Human Animals and Insects Source Type: news
More News: Insect Bites & Stings | International Medicine & Public Health | Physiology