2. Prefrontal Cortex and Striatum Hubs: Integrating Information From Reward, Cognitive, and Motor Control Regions

The cortico-cortical and cortico-basal ganglia networks are central to incentive-based learning and good decision making. There is growing consensus that obsessive-compulsive disorder, major depressive disorder, and addiction are manifestations of dysfunction of these networks. Behavioral responses to environmental cues depend not only on the ability to evaluate different aspects of reward, but also the ability to inhibit inappropriate choices. Integrating reward information with that involved in cognition and motor control is thus essential for developing motivational control and appropriately adaptive behaviors.
Source: Biological Psychiatry - Category: Psychiatry Authors: Source Type: research