Study: Beta-Blockers May Help Lung Cancer Patients Live Longer

Lung cancer patients who take beta-adrenergic receptor antagonists (beta-blockers) may survive longer and have a lower rate of tumor spread, according to a new study.
Source: Cancer Network - Category: Cancer & Oncology Source Type: news

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Advances in Systemic Therapy for Non-Small Cell Lung Cancer
Source: Thoracic Surgery Clinics - Category: Cardiovascular & Thoracic Surgery Source Type: research
Nonintubated video-assisted thoracoscopic surgery (VATS) lobectomy to treat lung cancer has gained attention in recent decades, but there is very little literature on this topic. This review aims to explore the state-of-the-art, recent progress, and future prospects of this method. Its feasibility and safety have been demonstrated, and its potential benefits are faster postoperative recovery and fewer intubation-related complications. Nonintubated VATS lobectomy is a feasible and safe alternative for lung cancer treatment. This work provides information for those who would like to start using this technique and want a more...
Source: Thoracic Surgery Clinics - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
Wedge resection in peripheral lung cancer is considered a suboptimal procedure. However, in elderly and/or frail patients it is a reliable and safer alternative. This procedure can be easily performed under nonintubated anesthesia, allowing the recruitment of patients considered otherwise marginal for a surgical treatment. Nonintubated anesthesia can reduce lung trauma, operative time, postoperative morbidity, hospital stay, and global expenses. Furthermore, nonintubated anesthesia produces less immunologic impairment and this may affect postoperative oncological long-term results. Wedge lung resection through nonintubated...
Source: Thoracic Surgery Clinics - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
In conclusion, TOP2A, CCNB1, BIRC5, miR‑21‑5p, miR‑193b‑3p, miR‑210‑3p and miR‑31‑5p may therefore serve as important biomarkers and diagnostic targets for NSCLC. PMID: 31746439 [PubMed - as supplied by publisher]
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Clinicopathological features and diagnostic methods of ALK fusion‑positive non‑small cell lung cancer in Korea. Oncol Rep. 2019 Nov 04;: Authors: Chang WC, Kim HK, Shin BK Abstract Lung cancer is one of the most common malignancies and the leading cause of cancer‑associated mortality in Korea. A significant amount of effort has been put into the development of new and more effective treatments and biological markers for the prediction of therapeutic responses, which has led to the identification of various genetic changes in cancer, that are the so‑called 'growth drivers' of carcinogenesis. Cer...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Exploratory study on application of MALDI‑TOF‑MS to detect serum and urine peptides related to small cell lung carcinoma. Mol Med Rep. 2019 Nov 05;: Authors: Lv P, Liu Z, Xu B, Tang C, Li X, Qin H, Yang S, Gao H, He K, Liu X Abstract Matrix‑assisted laser desorption/ionization time‑of‑flight mass spectrometry (MALDI‑TOF‑MS) was employed to analyze differential serum and urine peptides in patients with small cell lung cancer (SCLC) and healthy individuals, and SCLC diagnostic classification models were constructed. Serum and urine samples from 72 patients with SCLC, age‑ and gender...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Liu M, Li Z, Yao W, Zeng X, Wang L, Cheng J, Ma B, Zhang R, Min W, Wang H Abstract Previous studies suggest that radiotherapy (RT) can induce immune activation, which not only reduces the progression of tumors, but also causes the release of tumor antigens. The combination of RT and immune checkpoint blockade, such as the inhibition of programmed cell death 1 (PD‑1) and programmed cell death ligand 1 (PD‑L1), has been demonstrated to yield impressive response rates. However, a substantial proportion of patients develop resistance such therapies. Previous studies have shown that indoleamine 2,3‑dioxyg...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Publication date: Available online 21 November 2019Source: Arabian Journal of ChemistryAuthor(s): K. Lingaraju, H. Raja Naika, H. Nagabhushana, K. Jayanna, S. Devaraja, G. NagarajuAbstractNickel oxide Nanoparticles (NiO NPs) were synthesized from E.heterophylla (L.) leaves extract act as reducing/ capping agent by biosynthesis process. Further the synthesized NiO NPs was subjected for structural, optical and biological properties. The XRD pattern of NiO NPS exhibit face centred cubic (FCC) crystalline structure. The UV-DR spectrum of biosynthesized NiO NPs exhibited optical properties with well-defined at 321 nm and its ex...
Source: Arabian Journal of Chemistry - Category: Chemistry Source Type: research
(Reuters Health) – Even among smokers, people who eat more fiber and yogurt may be less likely to develop lung cancer than those who don't consume much of these foods, a research review suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
ConclusionsNetwork pharmacology analysis revealed that the compounds isoquercitrin, quercitrin, berberine, chlorogenic acid and caffeic acid showed strong synergistic interactions with the cancer-related targets and pathways. It could be concluded that N. domestica Thunb. constituents affect both apoptosis and Akt-signaling pathways during the stages of early and intermediate adenoma through interaction with the targets CASP3 and MAPK1 (ErC2) while during the stages of late adenoma and carcinoma, the compounds acts through the p53 and ErbB signaling pathways.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
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