Pick a Tag and Explore the Functions of Your Pet Protein.

Pick a Tag and Explore the Functions of Your Pet Protein. Trends Biotechnol. 2019 Apr 26;: Authors: Vandemoortele G, Eyckerman S, Gevaert K Abstract Protein tags have been essential for advancing our knowledge of the function of proteins, their localization, and the mapping of their interaction partners. Expressing epitope-tagged proteins has become a standard practice in every life science laboratory and, thus, continues to enable new studies. In recent years, several new tagging moieties have entered the limelight, many of them bringing new functionalities, such as targeted protein degradation, accurate quantification, and proximity labeling. Other novel tags aim at tackling research questions in challenging niches. In this review, we elaborate on recently introduced tags and the opportunities they provide for future research endeavors. In addition, we highlight how the genome-engineering revolution may boost the field of protein tags. PMID: 31036349 [PubMed - as supplied by publisher]
Source: Trends in Biotechnology - Category: Biotechnology Authors: Tags: Trends Biotechnol Source Type: research