Applying a multiplexed primer extension method on dried blood spots increased the detection of carriers at risk of glucose-6-phosphate dehydrogenase deficiency in newborn screening program.

CONCLUSIONS: Our approach could significantly increase the detection rate of male patients and female carriers with a reasonable cost and a reasonable number of clinic referrals. PMID: 31022393 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31022393?dopt=Abstract

Source: International Journal of Clinical Chemistry - April 21, 2019 Category: Chemistry Authors: Chiu YH, Chen HJ, Chang YC, Liu YN, Kao SM, Liu MY, Weng YY, Hsiao KJ, Liu TT Tags: Clin Chim Acta Source Type: research