Identification and structural characterization of the stress degradation products of omeprazole using Q-TOF-LC-ESI-MS/MS and NMR experiments: evaluation of the toxicity of the degradation products

New J. Chem., 2019, Advance Article DOI: 10.1039/C9NJ00932A, PaperG. Shankar, Roshan M. Borkar, Suresh Udutha, M. Kanakaraju, G. Sai Charan, S. Misra, R. Srinivas Omeprazole (OMP), a prototype proton pump inhibitor used for the treatment of peptic ulcers and gastroesophageal reflux disease (GERD), was subjected to forced degradation studies as per ICH guidelines Q1A (R2). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - New J. Chem. latest articles - April 25, 2019 Category: Chemistry Authors: G. Shankar Source Type: research