Multiple antigen-engineered DC vaccines with or without IFN α to promote antitumor immunity in melanoma

ConclusionsDC vaccines are a safe and reliable platform for promoting antitumor immunity. This combination with one month of high dose IFN α did not improve outcomes. Immune biomarker analysis in the blood identified several predictive and prognostic biomarkers for further analysis, including MDSC.Trial registrationNCT01622933.
Source: Journal for Immunotherapy of Cancer - Category: Cancer & Oncology Source Type: research