Effect of Implantation Site on Outcome of Tissue-Engineered Vascular Grafts.

CONCLUSION: Our PCL grafts in the carotid position were well endothelialised with early cellular infiltration, higher compliance, lower IH and calcification compared to the similar grafts implanted in the aortic position. However, there was a higher occlusion rate compared to our abdominal aorta series. Anatomical position, compliance mismatch, flow conditions may answer the difference in patency seen.
PMID: 31004790 [PubMed - as supplied by publisher]

Source: European Journal of Pharmaceutics and Biopharmaceutics - April 16, 2019 Category: Drugs & Pharmacology Authors: Sologashvili T, Saat SA, Tille JC, De Valence S, Mugnai D, Pierre Giliberto J, Dillon J, Yakub A, Dimon Z, Gurny R, Walpoth BH, Moeller M Tags: Eur J Pharm Biopharm Source Type: research