Temporal Pattern of Growth Differentiation Factor-15 Protein After Acute Coronary Syndrome (From the BIOMArCS Study)

Growth differentiation factor-15 (GDF-15) has appeared as a promising biomarker with strong predictive abilities in acute coronary syndrome (ACS). However, studies are solely based on single measurements in the acute phase of an ACS event. The way GDF-15 patterns in post ACS patients behave on the long term is largely unknown. We conducted a nested case-control study within our multicenter, prospective, observational biomarker study (BIOMArCS) of 844 ACS patients. Following an index ACS event, high-frequency blood sampling was performed during 1-year of follow-up.

Source: The American Journal of Cardiology - April 17, 2019 Category: Cardiology Authors: Nermina Buljubasic, Maxime M. Vroegindewey, Rohit M. Oemrawsingh, Folkert W. Asselbergs, Etienne Cramer, Anho Liem, Pim van der Harst, Arthur Maas, Eelko Ronner, Carl Schotborgh, Alexander J. Wardeh, K. Martijn Akkerhuis, Eric Boersma, for the BIOMArCS in Source Type: research