The Effects of Vasoconstriction And Volume Expansion on Veno-Arterial ECMO Flow

Conclusions: In a circulation completely dependent on ECMO support, maximum achievable flow directly depended on the vascular factors governing venous return—i.e., closing conditions, stressed vascular volume and the elastance and resistive properties of the vasculature. Both treatments increased maximum achievable ECMO flow at stable DO2, via increases in stressed volume by different mechanisms. Vascular resistance and pump afterload decreased with Volume Expansion.
Source: Shock - Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research