As Ebola Cases Rise in Congo, the W.H.O. Declines to Issue Emergency Declaration
The epidemic shows no signs of abating. In the eight-month-old outbreak, the highest number of cases recorded in a single day occurred this week.
[AfricaFocus] "Despite a worsening Ebola epidemic in the Democratic Republic of Congo, the World Health Organization on Friday again decided not to declare the outbreak a global health emergency. While expressing ´deep concern´ about the number of increasing cases in parts of Congo, and the potential risk of the disease spreading to neighboring countries, the W.H.O. said the epidemic did not meet the criteria for declaring an international public health emergency." - New York Times, April 12, 2019 (http:// ti
[MSF] New York -The international medical humanitarian organization Doctors Without Borders/M édecins Sans Frontières (MSF) made the following statement after the World Health Organization decided today to not declare a Public Health Emergency of International Concern for the ongoing Ebola outbreak in the Democratic Republic of Congo (DRC).
Source: World Health Organization (WHO). Published: 4/12/2019. This four-page report provides information about preliminary analysis that was completed with the aim to better understand whether or not the rVSV-ZEBOV-GP candidate vaccine is effective and is contributing to prevent cases of Ebola virus disease when delivered using the ring vaccination strategy. This experimental Ebola vaccine is being used to try to contain the outbreak in the Democratic Republic of the Congo, and is protective 97.5 percent of the time. These early results confirm previous observations of high efficacy of rVSV-ZEBOV-GP Ebola vaccine against disease. (PDF)
In this study, we evaluated ATA as a potential antiviral drug against ZIKV replication. The antiviral activity of ATA against ZIKV replication in vitro showed median inhibitory concentrations (IC50) of 13.87 ± 1.09 μM and 33.33 ± 1.13 μM in Vero and A549 cells, respectively; without showing any cytotoxic effect in both cell lines (median cytotoxic concentration (CC50)> 1,000 μM). Moreover, ATA protected both cell types from ZIKV-induced cytopathic effect (CPE) and apoptosis in a time- and concentration-dependent manner. In addition, pre-treatment of Vero cells with ATA for up to 72 h also resulted...
Adriano Queiroz1, Isabella Fernanda Dantas Pinto2, Maricélia Lima3, Marta Giovanetti1,4, Jaqueline Goes de Jesus1, Joilson Xavier1, Fernanda Khouri Barreto5, Gisele André Baptista Canuto6, Helineide Ramos do Amaral7, Ana Maria Bispo de Filippis4, Denise Lima Mascarenhas8, Melissa Barreto Falcão8, Normeide Pedreira Santos8, Vasco Ariston de Carvalho Azevedo9, Marcos Yukio Yoshinaga2*, Sayuri Miyamoto2 and Luiz Carlos Junior Alcantara1,4,10* 1Laboratório de Patologia Experimental, Instituto Gonçalo Moniz, Salvador, Brazil 2Departamento de Bioquímica, Instituto de Quími...
[Deutsche Welle] The Ebola outbreak in eastern Democratic Republic of the Congo has become difficult to contain. Many locals distrust health authorities trying to combat the epidemic, which poses a significant challenge for their work.
[VOA] The World Health Organization says insecurity and community mistrust in the Democratic Republic of Congo's conflict-ridden North Kivu Province are major impediments to international health efforts to bring the deadly Ebola outbreak under control. Latest official figures put the number of Ebola cases in the Eastern DRC at 1,089, including 679 deaths.
go RM Abstract Understanding risk factors for Ebola transmission is key for effective prediction and design of interventions. We used data on 860 cases in 129 chains of transmission from the latter half of the 2013-16 Ebola outbreak in Guinea. Using negative binomial regression, we determined characteristics associated with the number of secondary cases resulting from each infected individual. We found that attending an Ebola Treatment Unit was associated with a 38% decrease in secondary cases (Incident rate ratio (IRR) 0.62, 95%CI: 0.38, 0.99) in individuals that did not survive. Unsafe burial was associated with...
[Thomson Reuters Foundation] London -By March 2019 Congo's Ebola outbreak surpassed 1,000 cases with a death toll of 629 and spread to the city of Bunia, the second-largest city in eastern Congo
Congo's Ebola epidemic has now exceeded 1,000 cases, the Health Ministry said on Monday, with a death toll of 629 in the world's second worst ever outbreak.Reuters Health Information