Reduction of blood pressure elevation by losartan in spontaneously hypertensive rats through suppression of LARG expression in vascular smooth muscle cells.

CONCLUSION: The study results showed that the reduction of BP elevation by losartan in SHRs occurs through the suppression of LARG expression and MYPT-1 phosphorylation in vascular smooth muscle cells. PMID: 30962047 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30962047?dopt=Abstract

Source: J Formos Med Assoc - April 4, 2019 Category: General Medicine Authors: Chiu WC, Chiang JY, Juang JM, Wu CK, Tsai CT, Tseng YZ, Su MJ, Chiang FT Tags: J Formos Med Assoc Source Type: research