"Serious global health threat" from superbug fungus

The drug-resistant fungus Candida auris has sickened hundreds of people across the United States and around the world
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news

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(Natural News) Candida auris is a “silent superbug” that’s already spreading across U.S. hospitals and nursing homes. The CDC has reported hundreds of infections across seven states, and is tracking over 1,000 “colonizations” where the fungal strain has infected human carriers who spread it to others. Notably, the CDC refuses to name which hospitals have...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Conclusion: The River Nile could be a new source for production of promising bioactive leading compound where antimicrobial and antiparasitic activities may be correlated. Introduction Nature is an exceptional resource of new biologically active compounds with an astonishing chemical diversity such as that found in plant species, animals, and microorganisms (Butler et al., 2014). Microbial diversity constitutes an infinite pool of novel chemistry, making up a valuable source for innovative biotechnology (Bérdy, 2005; Fenical and Jensen, 2006). The aquatic environment is now becoming more appreciated as a ri...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
THURSDAY, April 11, 2019 -- The United States has had more than 600 cases of infection with a type of fungus called a " serious global health threat " by the U.S. Centers for Disease Control and Prevention. The first U.S. cases of Candida auris...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
It began in 2009, when doctors in Tokyo swabbed the ear of a 70-year-old woman and found an unknown strain of fungus that can infect humans and, in severe cases, cause a blood infection in high-risk patients. It's called Candida auris.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
This study aims to investigate the efficiencies of seven methods in C. albicans biofilm EM extraction, namely vortexing plus ultrasonication (VU), formaldehyde plus vortexing and ultrasonication (Formaldehyde-VU), EDTA plus vortexing and ultrasonication (EDTA-VU), NaOH plus vortexing and ultrasonication (NaOH-VU), ethanol plus vortexing and ultrasonication (Ethanol-VU), ion exchange resin plus vortexing and ultrasonication (IER-VU)—including cation/anion-exchange resin plus vortexing and ultrasonication (CER/AER-VU)—under the static and dynamic states. Subsequently, the extracted metabolites are analyzed with t...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Raquel Ferrer-Espada1,2, Xiaojing Liu1,2, Xueping Sharon Goh1,2 and Tianhong Dai1,2* 1Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States 2Vaccine &Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States Polymicrobial biofilms, in which mixed microbial species are present, play a significant role in persistent infections. Furthermore, polymicrobial biofilms promote antibiotic resistance by allowing interspecies transfer of antibiotic resistance genes. In the present study, we investigated the effec...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study aimed to contribute to the need of finding new and more effective bioactive molecules against several of the earlier mentioned threats faced by human kind nowadays. For this, eighteen species from the Actinomycetales previously isolated from Erylus spp. sponges collected in Portuguese marine waters (Açores, Madeira, and continental shelf) were screened for antimicrobial, anti-cancer, anti-parasitic and anti-obesogenic activities. Materials and Methods Biological Material The bacteria under study belong to the order Actinomycetales within the phylum Actinobacteria and were isolated from marine sponges o...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Mariana Girão1,2, Inês Ribeiro1, Tiago Ribeiro1, Isabel C. Azevedo1, Filipe Pereira1, Ralph Urbatzka1, Pedro N. Leão1 and Maria F. Carvalho1* 1Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Porto, Portugal 2Department of Biology, Faculty of Sciences, University of Porto, Porto, Portugal Nature is the major reservoir of biologically active molecules. The urgent need of finding novel molecules for pharmaceutical application is prompting the research of underexplored environments, such as marine ecosystems. Here, we investigated cultivable actinobacteria asso...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In conclusion, we demonstrated that the selective boosting of lung innate immunity is a conceptually advantageous approach for improving the effectiveness of antibiotic treatment and fighting antibiotic-resistant bacteria. Introduction Pneumonia constitutes a major cause of death, morbidity and health resource use worldwide. The main causative agents identified in adult patients hospitalized for community-acquired pneumonia (CAP) are viruses (in 27–30% of cases, the most common being rhinovirus, influenza and coronavirus) and bacteria (14–23% of cases, with a marked predominance of Streptococcus pneumonia...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 3 April 2019Source: Journal of Molecular LiquidsAuthor(s): Nadjet Rezki, Salsabeel A. Al-Sodies, Hany E.A. Ahmed, Saleh Ihmaid, Mouslim Messali, Sahar Ahmed, Mohamed Reda AouadAbstractA focused library of new dicationic ionic liquids (DiILs) 6–41 appended pyridinium hydrazone and phenoxy side chain hybrids as counter cations were designed and synthesized, utilizing quaternization and metathesis reactions under both conventional and microwave irradiation. The novel DiILs 6–41 were fully characterized using different spectroscopic tools (1H, 13C, 19F, 11B, 31P NMR and mass spect...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
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