Visuospatial learning and memory in children pre- and posttemporal lobe resection: Patterns of localization and lateralization

Publication date: May 2019Source: Epilepsy & Behavior, Volume 94Author(s): Elizabeth Stewart, Mary Lou SmithAbstractIn children with epilepsy, the impact of surgery including or sparing the mesial temporal lobes (TLs) on visuospatial memory has not been thoroughly investigated, and a clear pattern of hemispheric lateralization has not been observed. The primary aim of this study was to examine visuospatial learning and memory outcomes in children with epilepsy prior to and one year after surgical excision, to determine whether outcomes differed as a function of the localization and lateralization of surgical excisions. Forty-six children who underwent unilateral TL surgery with sparing of the mesial structures (TL group, N = 21, 16 left) or including mesial structures (TL + M group, N = 25 children, 12 left) were retrospectively recruited. Outcomes on the Children's Memory Scale (CMS) Dot Locations subtest (learning, immediate, and delayed recall scores) were examined prior to and following epilepsy surgery. Results revealed significantly reduced visuospatial memory (delayed recall) in the TL + M compared with the TL group after surgery. Despite this significant postoperative difference, there was no significant change in learning, immediate, or delayed recall scores in either group. However, inspection of individual change scores showed that fewer children in the TL + M group improved in delayed recall after surgery (7.2%) compared with children in the TL...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research