Impact of Implantable Cardioverter-Defibrillator Interventions on All-Cause Mortality in Heart Failure Patients: A Meta-Analysis

Implantable cardioverter-defibrillators (ICDs) have a unique role in the primary and secondary prevention of sudden cardiac death. However, appropriate and inappropriate ICD interventions [antitachycardia pacing (ATP) or shocks] can result in deleterious effects. The aim of our study was to systematically review the existing data about the impact of ICD interventions on all-cause mortality in heart failure patients with reduced ejection fraction (HFrEF). We systematically searched MEDLINE (by using PubMed Web-based search engine) without any limits until September 30, 2017. After screening 17,752 records, a total of 17 studies met our inclusion criteria and were included in our meta-analysis. Our data showed that in patients with HFrEF, appropriate [hazard ratio (HR), 2.00; 95% confidence interval (CI), 1.52–2.63; P
Source: Cardiology in Review - Category: Cardiology Tags: Review Articles Source Type: research