Atelo-collagen type I bovine bone substitute and membrane in guided bone regeneration: A series of clinical cases and histopathological assessments.

Atelo-collagen type I bovine bone substitute and membrane in guided bone regeneration: A series of clinical cases and histopathological assessments. Histol Histopathol. 2019 Apr 01;:18108 Authors: Lucaciu O, Apostu D, Mester A, Campian RS, Gheban D, Miron RJ Abstract Absorbable atelo-collagen type 1 represents a new approach for guided bone regeneration with several reported advantages such as: osteoblast attachment, proliferation, mineralization potential, absorption of growth factors and inhibition of bacterial pathogen colonization. The aim of this study was to assess the clinical, radiological (preoperative width, re-entry width, gain), Periotest measurements and histologic benefits of atelo-collagen-derived bovine bone grafts (ImploBone) in combination with an atelo-collagen type I barrier membrane (ImploSorb) for guided bone regeneration (GBR) of atrophic alveolar crest in thirteen patients. Eleven patients underwent simultaneous GBR with implant insertion, two had initial GBR procedure followed by implant placement after 6 months of healing. Ridge augmentation was performed using an atelo-collagen membrane (ImploSorb, Bioimplon, Germany) and a combination of 50% ABBM (ImploBone, granule size 0.5-1mm, BioImplon Germany) mixed with 50% autologous bone. It was found that simultaneous GBR with implant placement resulted in a 45% gain at bone defect level (preoperative width 4.76±1.3 mm, re-entry width 6.91±1.1 mm, gain 2.16±1.9...
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research