Irritability and Its Clinical Utility in Major Depressive Disorder: Prediction of Individual-Level Acute-Phase Outcomes Using Early Changes in Irritability and Depression Severity.

CONCLUSIONS:: Irritability is an important symptom domain of major depressive disorder that is not fully reflected in depressive symptom severity measures. Early reductions in irritability, when combined with changes in depressive symptom severity, provide a robust estimate of likelihood of remission or no meaningful benefit in outpatients with major depression. PMID: 30922100 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30922100?dopt=Abstract

Source: The American Journal of Psychiatry - March 28, 2019 Category: Psychiatry Authors: Jha MK, Minhajuddin A, South C, Rush AJ, Trivedi MH Tags: Am J Psychiatry Source Type: research

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