Receptor for advanced glycation end-products and environmental exposure related obstructive airways disease: a systematic review

Conclusion
RAGE is a mediator of inflammation associated end-organ dysfunction such as obstructive airways disease. Soluble RAGE, a decoy receptor, may have a protective effect in some pulmonary processes. Overall, RAGE is biologically relevant in environmental exposure associated lung disease. Future investigations should focus on further understanding the role and therapeutic potential of RAGE in particulate matter exposure associated lung disease.

Source: European Respiratory Review - March 26, 2019 Category: Respiratory Medicine Authors: Haider, S. H., Oskuei, A., Crowley, G., Kwon, S., Lam, R., Riggs, J., Mikhail, M., Talusan, A., Veerappan, A., Kim, J. S., Caraher, E. J., Nolan, A. Tags: Epidemiology, occupational and environmental lung disease Review Source Type: research