FAM3C-YY1 axis is essential for TGF β-promoted proliferation and migration of human breast cancer MDA-MB-231 cells via the activation of HSF1.

In conclusion, FAM3C activated YY1-HSF1 signalling axis to promote the proliferation and migration of breast cancer cells. Furthermore, novel FAM3C-YY1-HSF1 pathway plays an important role in TGFβ-triggered proliferation and migration of human breast cancer MDA-MB-231 cells. PMID: 30887707 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30887707?dopt=Abstract

Source: J Cell Mol Med - March 18, 2019 Category: Molecular Biology Authors: Yang W, Feng B, Meng Y, Wang J, Geng B, Cui Q, Zhang H, Yang Y, Yang J Tags: J Cell Mol Med Source Type: research