IRS1 ‐ rs10498210 G/A and CCR5‐59029 A/G polymorphisms in patients with type 2 diabetes in Kurdistan

ConclusionAccording to the results of this study, the presence of AA genotype in bothCCR5 andIRS1 is associated with type 2 diabetes. There was no significant association between AG or GG genotypes with type 2 diabetes.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research

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CONCLUSION: ATV inhibited ROS generation and activated IL-1 β/IL-6 secretion in PBMNC of diabetes patients. Its effect was not affected by the hyperglymemia. PMID: 31416412 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Authors: Phan K, Smith SD Abstract Background: Topical steroids have been previously associated with potential for hyperglycemia and glucosuria, and thought to have a relatively safe side effect profile. In prolonged use, there is the potential for steroids to be absorbed through the skin and eventually reach systemic circulation. We aimed to investigate the potential association between topical corticosteroid use and development of diabetes, we performed a systematic review and meta-analysis of available case-control data in the literature. Methods: Electronic database searches was performed to identify studies co...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
The objective of the present study was to investigate the association between hair and urine Al levels and obesity.MethodsA total of 206 lean and 205 obese non-occupationally exposed subjects (30-50 y.o.) were enrolled in the study. Hair and urine Al levels were assessed with ICP-MS. Laboratory quality control was performed using the certified reference materials of human hair, plasma, and urine.ResultsHair and urinary Al levels in obese subjects were significantly higher by 31% and 46% compared to the control levels, respectively. The presence of hypertension (41% cases), atherosclerosis (8%), type 2 diabetes melli...
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
Authors: Abstract [This corrects the article doi: 10.1590/2175-8239-jbn-2018-0200]. PMID: 31419278 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD), the most common liver disease, is characterized by accumulation of fat (>5% of the liver tissue), in the absence of alcohol abuse or other chronic liver diseases. Its prevalence is increasing because of obesity, metabolic syndrome or Type 2 Diabetes Mellitus (T2DM). NAFLD can cause liver inflammation and progress to Non-Alcoholic Steatohepatitis (NASH), fibrosis, cirrhosis or Hepatocellular Cancer (HCC). Nevertheless, Cardiovascular Disease (CVD) is the most common cause of morbidity and mortality in NAFLD/NASH patients. Current guidelines suggest the use of p...
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research
Publication date: Available online 16 August 2019Source: Journal of Clinical &Translational EndocrinologyAuthor(s): Magdy M. Allam, Hanaa T. El-ZawawyAbstractBackgroundRemission of Type 2 diabetes mellitus (DM) has been observed throughout the last few years, yet factors associated with remission through non-surgical approaches are still unclear. So, the factors associated with type 2 DM remission were investigatedMethodsout 670 patients, 63 patients gained non-surgical remission of type 2 DM (defined according to ADA criteria), and 396 patients served as control matched for age, sex, and BMI. The records of patients w...
Source: Journal of Clinical and Translational Endocrinology - Category: Endocrinology Source Type: research
TYPE 2 diabetes is considered a very serious condition and left untreated it could lead to serious health complications. Some simple lifestyle changes can help prevent or control the condition. When it comes to your first meal of the day, what is the best breakfast to eat?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
TYPE 2 diabetes is a condition characterised by high blood sugar, insulin resistance, and relative lack of insulin. A person ’s breath can indicate if they are risk of developing the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Chen W, Li P, Wang G, Chen Y, Wang B, Chen M Abstract OBJECTIVES: To evaluate the efficacy and safety of ipragliflozin as add-on therapy to metformin in patients with type 2 diabetes mellitus. METHODS: Systematic literature searches were performed in several databases across PubMed, the Cochrane Central Register of Controlled Trials, Embase, Medline, ClinicalTrials.gov, PsycINFO, and Web of Science from inception to 12 March 2019. After the extraction of data from eligible studies, randomized controlled trials (RCTs) were assessed for quality and analyzed statistically. Standardize...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
TYPE 2 diabetics are aware they need to be extra vigilant with what they put in their mouths. We all know about the dangers of sugar and even though it does not directly affect the condition, it can lead to weight gain and obesity risk. How can you still enjoy your favourite treats without the health risk of added sugars?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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