cTBS over contralesional homologue areas deteriorates speech output in isolated Apraxia of Speech after stroke

Apraxia of speech (AOS) is an impairment of motor speech planning/programming, characterized by a combination of phonemic segmental changes and articulatory distortions [1]. AOS is most often accompanied by aphasia, whereas isolated forms may rarely occur after focal damage to the left precentral gyrus [1]. How AOS recovers after brain damage is poorly understood [2]. In particular, it is not known whether recovery of AOS solely depends on the functional reorganisation of perilesional areas [3, 4], or whether it also depends on the compensation through contralesional homologue areas.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 17, 2019 Category: Neurology Authors: Brigitte C. Kaufmann, Manuela Pastore-Wapp, Maria L übeck, Monica Koenig, Stephan Bohlhalter, Tim Vanbellingen, Dario Cazzoli, Thomas Nyffeler Source Type: research