The role of pregnant women with rash in the Zika virus sentinel surveillance

CONCLUSIONS Our results allowed the characterization of pregnant women exposed to ZIKV and the outcome of pregnancy.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research

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Following publication of the original article [1], the author mentioned that two additional NIH staff were involved in the development of the protocol who did not receive recognition in the Acknowledgments sec...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Correction Source Type: research
Lu Lu Recently, Zika virus (ZIKV) has attracted much attention in consideration of its association with severe neurological complications including fetal microcephaly. However, there are currently no prophylactic vaccines or therapeutic drugs approved for clinical treatments of ZIKV infection. To determine the potential anti-ZIKV inhibitors, we screened a library of clinical drugs with good safety profiles. Erythromycin estolate (Ery-Est), one of the macrolide antibiotics, was found to effectively inhibit ZIKV infection in different cell types and significantly protect A129 mice from ZIKV-associated neurological sign...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
AbstractPuerto Rico was hit by two major hurricanes in September 2017 causing great devastation, losing over 90% of the power grid, wireless communication and access to potable water, and destroying many homes. Our research programs: Puerto Rico Testsite for Exploring Contamination Threats (PROTECT), Center for Research on Early Childhood Exposure and Development in Puerto Rico (CRECE), Zika in Infants and Pregnancy (ZIP), and Environmental Influences on Child Health Outcomes (ECHO) are ongoing observational cohort studies that have been investigating environmental risk factors for perinatal health outcomes among Puerto Ri...
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
CONCLUSION: For a cohort of New York City women, antenatal Zika virus infection was associated with an increased risk of having an SGA neonate, but not preterm birth or lower mean birth weight of term neonates. This supports a putative association between Zika virus infection during pregnancy and SGA. PMID: 31698388 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
th Du Chen Zika virus (ZIKV) infection during pregnancy leads to severe congenital Zika syndrome, which includes microcephaly and other neurological malformations. No therapeutic agents have, so far, been approved for the treatment of ZIKV infection in humans; as such, there is a need for a continuous effort to develop effective and safe antiviral drugs to treat ZIKV-caused diseases. After screening a natural product library, we have herein identified four natural products with anti-ZIKV activity in Vero E6 cells, including gossypol, curcumin, digitonin, and conessine. Except for curcumin, the other three natura...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Source: Centers for Disease Control and Prevention (CDC). Published: 11/2019. This web page, updated in November 2019, provides guidance for women and their partners who live in or travel to areas with a Zika outbreak or other areas with risk of Zika to plan their pregnancies in the context of the risk of Zika. Healthcare providers should counsel couples considering pregnancy about plans for travel to or those living in areas with risk of Zika. The page includes clinician resources. (Text)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
ConclusionStudies of vaccines against ZIKV are progressing positively, and in their designs, modifications of the antigens are being considered so that they do not cause cross reactions with other flaviviruses that can cause complications in people previously exposed to other flaviviruses
Source: Current Tropical Medicine Reports - Category: Tropical Medicine Source Type: research
Research suggests a new way that Zika infection in mice promotes microcephaly
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
Authors: Wilder-Smith A, Preet R, Brickley EB, Ximenes RAA, Miranda-Filho DB, Turchi Martelli CM, Araújo TVB, Montarroyos UR, Moreira ME, Turchi MD, Solomon T, Jacobs BC, Villamizar CP, Osorio L, de Filipps AMB, Neyts J, Kaptein S, Huits R, Ariën KK, Willison HJ, Edgar JM, Barnett SC, Peeling R, Boeras D, Guzman MG, de Silva AM, Falconar AK, Romero-Vivas C, Gaunt MW, Sette A, Weiskopf D, Lambrechts L, Dolk H, Morris JK, Orioli IM, O'Reilly KM, Yakob L, Rocklöv J, Soares C, Ferreira MLB, Franca RFO, Precioso AR, Logan J, Lang T, Jamieson N, Massad E Abstract Zika Preparedness Latin American Network ...
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Letter To The Editor Source Type: research
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