Associations between paraoxonase 1 (PON1) polymorphisms and susceptibility and PON1 activity in rheumatoid arthritis patients, and comparison of PON1 activity in patients and controls: a meta-analysis

ConclusionsWe found no association between the PON1 Q192R and L55M polymorphisms and susceptibility to RA, while PON1 Q192R polymorphism was associated with PON1 activity in RA patients; we found significantly lower PON1 activity in RA patients.Key points•PON1 Q192R polymorphism is associated with PON1 activity in RA patients..•PON1 activity is significantly lower in RA patients..
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research