Biological effects in normal cells exposed to FLASH dose rate protons.
CONCLUSIONS: In normal lung fibroblasts proton dose rate had little impact on acute effects, but significantly influenced the expression of long-term biological responses in vitro. Compared to conventional dose rates, protons delivered at FLASH dose rates mitigated such delayed detrimental effects.
PMID: 30850209 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Buonanno M, Grilj V, Brenner DJ Tags: Radiother Oncol Source Type: research