Cysteine-rich intestinal protein 1 suppresses apoptosis and chemosensitivity to 5-fluorouracil in colorectal cancer through ubiquitin-mediated Fas degradation.

CONCLUSION: The current research reveals a vital role of CRIP1 in CRC progression, which provide a novel target for clinical drug resistance of colorectal cancer and undoubtedly contributing to the therapeutic strategies in CRC.
PMID: 30850009 [PubMed - in process]

Source: Clinical Colorectal Cancer - March 7, 2019 Category: Cancer & Oncology Authors: Zhang L, Zhou R, Zhang W, Yao X, Li W, Xu L, Sun X, Zhao L Tags: J Exp Clin Cancer Res Source Type: research