Contribution of sialic acids to integrin α5β1 functioning in melanoma cells

ConclusionsOur data suggest that in primary melanoma cells integrin α5β1 action is more likely dependent on its glycosylation profile, i.e. the presence of SA residues, which influence (decreased) their invasion properties and may facilitate malignant melanoma progression.
Source: Advances in Medical Sciences - Category: Biomedical Science Source Type: research