MEK5 promotes lung adenocarcinoma

Lung cancer represents the leading cause of cancer death worldwide [1]. Because of that, intense efforts are being devoted to the development of novel therapeutic strategies to fight the disease [2]. In this respect, identification of new oncogenic drivers offers therapeutic opportunities in tumours in which those molecules or other cooperating elements play a pathophysiological role. Here, we show that the MEK5 mitogen-activated protein kinase kinase has a pivotal role in lung cancer.

Source: European Respiratory Journal - February 28, 2019 Category: Respiratory Medicine Authors: Sanchez-Fdez, A., Ortiz-Ruiz, M. J., Re-Louhau, M. F., Ramos, I., Blanco-Munez, O., Ludena, D., Abad, M., Sanchez-Martin, M., Pandiella, A., Esparis-Ogando, A. Tags: Original Articles: Research letters Source Type: research