Polyneuropathies and Chronic Inflammatory Demyelinating Polyradiculoneuropathy in Multiple Sclerosis

Conclusion(1 Polyneuropathies occurring in MS contribute to neurological disability. 2) Diagnosing polyneuropathies in people with MS is challenging and, likely, under-diagnosed. Recognition is important as some polyneuropathies (e.g., CIDP) are treatable.3) The probable over-representation of inflammatory neuropathy (especially CIDP) in MS suggests a shared dysimmune pathogenesis, supported by autoantibodies to neurofascin-155.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research