Spatial Dose Patterns Associated with Radiation Pneumonitis in a Randomized Trial Comparing Intensity-Modulated Radiation Therapy with Passive Scattering Proton Therapy for Locally Advanced Non-Small Cell Lung Cancer
We explored spatial dose patterns associated with symptomatic radiation pneumonitis (RP) in patients with non-small-cell lung cancer given either intensity-modulated photon therapy or passive scattering proton therapy. A dose distribution analysis highlighted regional dose differences associated with both RP status and treatment modality, showing that regions spared with protons are complementary to those correlated with RP; these results can be useful for clinical practice and for designing future trials to minimize RP.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Giuseppe Palma, Serena Monti, Ting Xu, Emanuele Scifoni, Pei Yang, Stephen M. Hahn, Marco Durante, Radhe Mohan, Zhongxing Liao, Laura Cella Tags: Physics Contribution Source Type: research
More News: Biology | Cancer | Cancer & Oncology | Intensity-Modulated Radiation Therapy | Lung Cancer | Non-Small Cell Lung Cancer | Physics | Proton Therapy | Radiation Therapy | Radiology