Non ‐invasive analysis of tumor mutation profiles and druggable mutations by sequencing of cell free DNA of Chinese metastatic breast cancer patients

ConclusionTargeted deep sequencing of cell free DNA is a highly sensitive, noninvasive method to depict tumor mutation profiles, identify druggable mutations in MBC, and predict patient outcome. Our study shed light on the utility of ctDNA as noninvasive “liquid biopsy” in the management of MBC.

https://onlinelibrary.wiley.com/doi/abs/10.1111/1759-7714.13002?af=R

Source: Thoracic Cancer - February 21, 2019 Category: Cancer & Oncology Authors: Shunying Li, Xiaobao Wang, Yuquan Li, Hongna Lai, Yujie Liu, Liang Jin Tags: ORIGINAL ARTICLE Source Type: research