Translating transcription: proteomics in chronic rhinosinusitis with nasal polyps reveals significant discordance with messenger RNA expression.

CONCLUSION: Proteomic analysis in CRSwNP has revealed novel disease-associated proteins and pathways, yet correlates poorly with transcriptomic data. The increasing availability of proteomic arrays opens the door to new potential explanatory mechanisms in CRSwNP and suggests that mRNA based studies should be validated with protein analysis.
PMID: 30775848 [PubMed - as supplied by publisher]

Source: Genomics Proteomics ... - February 18, 2019 Category: Genetics & Stem Cells Authors: Workman AD, Nocera AL, Mueller SK, Otu HH, Libermann TA, Bleier BS Tags: Int Forum Allergy Rhinol Source Type: research