Genes, Vol. 10, Pages 154: PheWAS-Based Systems Genetics Methods for Anti-Breast Cancer Drug Discovery

In this study, we aimed to establish two effective strategies for identifying breast cancer genes based on the systems genetics algorithm. As a result, we found that the GeneRank-based strategy, which combines the prognostic phenotype-based gene-dependent network with the phenotypic-related PheWAS data, can promote the identification of breast cancer genes and the discovery of anti-breast cancer drugs.
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Letter Source Type: research