Formoterol counteracts the inhibitory effect of cigarette smoke on glucocorticoid-induced leucine zipper (GILZ) transactivation in human bronchial smooth muscle cells.

This study shed light on a mechanism underlying complementary interactions between LABA and inhaled GC that could be relevant in smokers with asthma and COPD. PMID: 30753866 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30753866?dopt=Abstract

Source: European Journal of Pharmacology - February 9, 2019 Category: Drugs & Pharmacology Authors: Marchini G, Carnevali S, Facchinetti F Tags: Eur J Pharmacol Source Type: research