Tight junction proteins at the blood-brain barrier: far more than claudin-5.

In conclusion, this complete Cldn/TAMP profile demonstrates the presence of up to a dozen TJ proteins in brain capillaries. Mouse and human share a similar and complex TJ profile in vivo, but this complexity is widely lost under in vitro conditions.
PMID: 30734065 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Life Sciences : CMLS - February 7, 2019 Category: Cytology Authors: Berndt P, Winkler L, Cording J, Breitkreuz-Korff O, Rex A, Dithmer S, Rausch V, Blasig R, Richter M, Sporbert A, Wolburg H, Blasig IE, Haseloff RF Tags: Cell Mol Life Sci Source Type: research