Probability of carcinogenesis due to involved field and involved site radiation therapy techniques for supra- and infradiaphragmatic Hodgkin ’s disease

Hodgkin Lymphoma (HL) is a B-cell lymphoid malignancy usually affecting young adults 20 –34 years old (yr) [1]. Prognosis of HL patients is usually excellent, with a 5-year relative survival rate reaching 86.6% for patients diagnosed in the period 2008–2014 [2]. Radiation therapy (RT) has a key role in the management of HL patients [3,4]. However, the use of RT has been associate d with late effects, including the development of secondary malignancies [5–7]. HL patients present statically significant increased risk of developing second cancer for at least 40 yrs after irradiation [8].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research