TERT promoter mutations identify a high-risk group in metastasis-free advanced thyroid carcinoma

TERT promoter mutations are associated with adverse clinicopathological characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes. Nevertheless, most studies have pooled heterogeneous types of thyroid carcinomas  and have been conducted retrospectively. We investigated the association between TERT promoter mutations and recurrence in a prospective series of 173 intermediate- to high-risk patients with thyroid cancer.

Source: European Journal of Cancer - January 14, 2019 Category: Cancer & Oncology Authors: Claire Bournaud, Fran çoise Descotes, Myriam Decaussin-Petrucci, Julien Berthiller, Christelle de la Fouchardière, Anne-Laure Giraudet, Mireille Bertholon-Gregoire, Philip Robinson, Jean-Christophe Lifante, Jonathan Lopez, Françoise Borson-Chazot Tags: Original Research Source Type: research