Why we need a BI-RADS-like system for uterine tumors

Does radiology need a scoring system like BI-RADS for tracking uterine tumors?...Read more on AuntMinnie.comRelated Reading: Study shows uterine cancer prevalence after morcellation Comments: 2/4/2019 7:28:08 AMmedphys While a UI-RADS system would be a step in the right direction, there's a worse problem:  some ob/gyn offices use their own ultrasound units, and it's not obvious that any radiologist ever sees the images.  These ob/gyn offices have a financial motivation to NOT refer any patients for ultrasound in a radiology department.   2/4/2019 8:09:38 AMDr. DG from Toronto I am very sorry to hear your family's story.  Unfortunately, it is very difficult for imaging to differentiate between degenerating fibroids and malignant lesions.  Seems to me that the practice of "morcellation" of these tumors contradicts all reasonable surgical principles by dispersing tumor cells all over the peritoneal cavity and subjecting the patient to a surgical "Russian Roulette" given that a small percentage of large fibroids will be malignant.  Who came up with this idea?  Have they denounced the practice?  Is this still going on?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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The differential diagnosis of fibroids could be challenging with other uterine masses including adenomyomas or uterine cancers and sarcomas. Minimally Invasive procedures including morcellation mandates a thorough imaging and if possible histologic analyses. To date such a pathologic approach has a very poor accuracy, even conducted under ultrasound, MRI or hysteroscopic guidance. A targeted biopsy requires the development of state of the art imaging and robotics to enable a secure, reproducible, and accurate sampling.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Virtual Poster Session 2:  Basic Science/Research/Education (1:40 PM – 1:50 PM) 1:40 PM: STATION L Source Type: research
3D ultrasound imaging of the female pelvis is one of the most important recent advances in diagnostic imaging. Volume acquisitions can provide a large number of images of the pelvic organs simultaneously and in any plane or orientation desired. The coronal plane of the uterus is only visible when reconstructed from a volume and is key to imaging the uterus for indications such as uterine anomalies, IUD positioning, locations of fibroids and polyps, or early pregnancies. 3D ultrasonography has huge potential for evaluating infertile patients, performing difficult procedures under guidance, and studying patients with abnorma...
Source: Obstetrics and Gynecology Clinics - Category: OBGYN Authors: Source Type: research
In this study, we aimed to identify and determine the efficacy of serum biomarkers for the prompt diagnosis of ectopic pregnancy. For this purpose, the serum concentrations of progesterone, β human chorionic gonadotropin (β‑hCG) and cancer antigen‑125 (CA125) were detected by solid‑phase, competitive binding chemiluminescent enzyme immunoassays. Flow cytometry was used to analyze the percentage of CD3+ T cells in women with ectopic pregnancy. Pathological analysis of tubal and villus tissues was performed by hematoxylin and eosin (H&E) staining. After receiving an injection of methotrexate (MTX), patie...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Abstract OBJECTIVE: To assess the long-term outcome of post-menopausal women diagnosed with non-atypical endometrial hyperplasia (NEH). METHODS: It is a retrospective study of women aged 55 and older who underwent endometrial sampling in our large academic medical center between 1997 and 2008. Women diagnosed with NEH were included in the study group and were compared to women diagnosed with atrophic endometrium on endometrial sampling. Outcome data was obtained through February 2018. The main outcomes were the risk of progression to endometrial carcinoma and the risk of persistent endometrial hyperplasia (EH...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
AbstractPurpose of ReviewFor uterine cervical cancer, the recently revised International Federation of Gynecology and Obstetrics (FIGO) staging system (2018) incorporates imaging and pathology assessments in its staging. In this review we summarize the reported staging performances of conventional and novel imaging methods and provide an overview of promising novel imaging methods relevant for cervical cancer patient care.Recent FindingsDiagnostic imaging during the primary diagnostic work-up is recommended to better assess tumor extent and metastatic disease and is now reflected in the 2018 FIGO stages 3C1 and 3C2 (positi...
Source: Current Oncology Reports - Category: Cancer & Oncology Source Type: research
ConclusionCurettage for miscarriage or undesired pregnancy is not exempt from complications, such as hemorrhage, simple perforation, and infection. Intrauterine fallopian tube incarceration is uncommon but can affect fertility. This diagnosis is important to avoid destruction of the fimbriae and necrosis of the tube and also to reduce the risk of ectopic pregnancy.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
CONCLUSIONS: In the hands of experienced ultrasound examiners SA was superior to taking measurements for prediction of deep MI and CSI of endometrial cancer especially in grade 1-2 tumors. The mathematical models for prediction of high-risk cancer performed as expected. The best strategy to predict high-risk endometrial cancer was either to simply combine SA with biopsy grade or to use the subjective 2-step strategy, both having an accuracy of 80%. This article is protected by copyright. All rights reserved. PMID: 31225683 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
ConclusionThe pathogenesis of this endometrial cancer is complex, and its association with human papillomavirus does not explain its genesis.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Researchers at Western University, London Health Sciences Centre, and Lawson Health Research Institute, all in Canada, have developed and tested a new 3D ultrasound system. Designed to improve the accuracy of interstitial brachytherapy, a technique i...
Source: Medgadget - Category: Medical Devices Authors: Tags: Ob/Gyn Oncology Source Type: blogs
We report a case of misdiagnosed endometrial cancer by D&C, but with a positive cytopathological finding. Following that, a meta-analysis including 4,179 patients of endometrial diseases with cyto-histopathological results was performed to assess the value of the endometrial cytological method in endometrial cancer diagnosis. The pooled sensitivity and specificity of the cytological method in detecting endometrial atypical hyperplasia or cancer was 0.91[95% confidence interval (CI) 0.74–0.97] and 0.96 (95% CI 0.90–0.99), respectively. The pooled positive likelihood ratio and negative likelihood ratio was 25.4 (...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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