Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling-mediated muscular hypertrophy and myoblast differentiation

ConclusionRb1 and Rb2 upregulate myotube growth and myogenic differentiation through activating Akt/mTOR signaling and induce myogenic conversion of fibroblasts. Thus, our first finding indicates that Rb1 and Rb2 have strong potential as a helpful remedy to prevent and treat muscle atrophy, such as age-related muscular dystrophy.
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research