Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Conditions: Adult Anaplastic Astrocytoma; Adult Anaplastic Ependymoma; Adult Anaplastic Oligodendroglioma; Adult Brain Stem Glioma; Adult Diffuse Astrocytoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Mixed Glioma; Adult Oligodendroglioma; Adult Pilocytic Astrocytoma; Adult Pineal Gland Astrocytoma; Adult Subependymal Giant Cell Astrocytoma; Recurrent Adult Brain TumorInterventions: Radiation: Hyperfractionated radiation therapy; Radiation: Stereotactic radiosurgery; Drug: Alisertib; Procedure: Quality-of-life assessmentSponsors: Thomas Jefferson University; Millennium Pharmaceuticals, Inc.Not yet recruiting - verified November 2014

http://clinicaltrials.gov/ct2/show/NCT02186509?lup_s=10%2F21%2F2014&lup_d=30

Source: ClinicalTrials.gov - July 7, 2014 Category: Research Source Type: clinical trials