‘Big Food’ a major driver for obesity pandemic

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Publication date: 15 September 2019Source: Life Sciences, Volume 233Author(s): Ke Wang, Xiang-hua Yu, Ya-Jie Tang, Ya-ling Tang, Xin-hua LiangAbstractObesity has become pandemic and emerged as one of the most critical global health care problems worldwide since last century. Recent studies have demonstrated that there may be a causal link between obesity and higher risks and mortality of cancers, including prostate, breast, colon, and thyroid cancers, head and neck cancer (HNC). This review focuses on the relationship between obesity and HNC, and the molecular mechanism of abnormal lipid metabolism in HNC. Elucidating the ...
Source: Life Sciences - Category: Biology Source Type: research
ConclusionThe present SR provides state-of-the-art information about the use of metabolomics as an approach to understanding the dynamics of metabolic processes involved in human obesity and emphasizes metabolic signatures related to obesity phenotypes.
Source: Metabolomics - Category: Biology Source Type: research
Authors: Ayers D, Boughanem H, Macías-González M Abstract The World Health Organization (WHO) considers that obesity has reached proportions of pandemic. Experts also insist on the importance of considering obesity as a chronic disease and one of the main contributors to the worldwide burden of other nontransmissible chronic diseases, which have a great impact on health, lifestyle, and economic cost. One of the most current challenges of biomedical science faces is to understand the origin of the chronic nontransmissible diseases, such as obesity and cancer. There is a large evidence, both in epidemio...
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
Katherine Samaras1,2,3*, Henrik Tevaerai4, Michel Goldman5, Johannes le Coutre6,7 and Jeff M. P. Holly8 1Department of Endocrinology, St Vincent's Hospital, Darlinghurst, NSW, Australia 2Diabetes and Metabolism, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia 3St Vincent's Hospital, St Vincent's Clinical School, Darlinghurst, NSW, Australia 4Bern University Hospital, Bern, Switzerland 5Institute for Interdisciplinary Innovation in Healthcare, Universite Libre de Bruxelles, Bruxelles, Belgium 6Department of Medicine, Imperial College London, London, United Kingdom 7Nes...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusions: Bariatric surgery appears to be capable of partially reversing the obesity-related epigenome. The identification of potential epigenetic biomarkers predictive for the success of bariatric surgery may open new doors to personalized therapy for severe obesity. Introduction Obesity is currently a huge healthcare problem, worldwide, and is a risk factor for several diseases such as type 2 diabetes (T2D), cardiovascular disease and cancer (1). As the prevalence of obesity reaches pandemic proportions, this metabolic disease is estimated to become the biggest cause of mortality in the near future (2). In fact,...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Midlife obesity has recently been identified as a global pandemic (1). Morbidities and mortalities attributable to excess adiposity include atherosclerosis, type 2 diabetes (T2D) (2), certain cancers (3), and dementia (4), each of which has reached epidemic proportions on its own. It is no exaggeration to state that T2D and...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Commentaries Source Type: research
Obesity is one of the major pandemics of the 21st century. In 2013 –2014, the prevalence of obesity in the US was>35% among men and 40% among women [1]. The World Health Organization (WHO) reported that 39% of men and 39% of women were overweight, and 11% of men and 15% of women were obese in 2016. Thus, approximately 2 billion adults worldwide were overweight and, among them, more than half a billion were obese [2]. Obesity is a chronic disease adversely affecting the quality of life and is associated with many comorbidities, like hypertension, dyslipidemia, type 2 diabetes (T2DM), cardiovascular disease (CVD), n...
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
Overweight and obesity constitute a global pandemic with devastating consequences that affect>2 billion people. Obesity plays a central role in morbidity and mortality of diseases of multiple organs and systems, and it is a major contributor to the growing incidence of cancer. There is now sufficient level of evidence for the association between overweight and 11 types of cancer, among which are two of the most common cancers worldwide, those of the colorectum and postmenopausal breast. Sedentary lifestyle, unhealthy diet, and excessive alcohol intake also account for the burden of cancer by promoting obesity.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
Conclusion: Preoperative endoscopy should be performed in order to detect GERD, BE, and potential carcinomas of the upper gastrointestinal tract before undergoing bariatric surgery. The long-term monitoring after SG is essential.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conclusion: Preoperative endoscopy should be performed in order to detect GERD, BE, and potential carcinomas of the upper gastrointestinal tract before undergoing bariatric surgery. The long-term monitoring after SG is essential.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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