Live attenuated varicella-zoster virus vaccine does not induce HIV target cell activation

CONCLUSION. This study provides the first evidence to our knowledge about the effects of VZV vaccination on human mucosal IA status and supports further evaluation of VZV as a potential vector for an HIV vaccine. TRIAL REGISTRATION. ClinicalTrials.gov NCT02514018. FUNDING. Primary support from the Canadian Institutes for Health Research (CIHR). For other sources, see Acknowledgments.

Source: Journal of Clinical Investigation - January 23, 2019 Category: Biomedical Science Authors: Catia T. Perciani, Bashir Farah, Rupert Kaul, Mario A. Ostrowski, Salaheddin M. Mahmud, Omu Anzala, Walter Jaoko, KAVI-ICR Team, Kelly S. MacDonald Source Type: research