Thyroglobulin is markedly elevated in 6-24-month-old infants at both low and high iodine intakes and suggests a narrow optimal iodine intake range.

Conclusions Tg is a sensitive biomarker of iodine intake in 6-24-month-old infants and follows a U-shaped relationship with iodine intake, suggesting a relatively narrow optimal intake range. Infants with low iodine intakes may be at an increased risk of subclinical thyroid dysfunction. In population monitoring of iodine deficiency or excess, assessment of iodine status using UIC and Tg may be valuable in this young age group. PMID: 30648484 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research