Iron handling by the human kidney: Glomerular filtration and tubular reabsorption both contribute to urinary iron excretion.

CONCLUSION: Our explorative study demonstrates that both glomerular filtration of elevated plasma iron levels and insufficient tubular iron reabsorption could increase urinary iron excretion and cause renal injury.
PMID: 30623722 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - January 9, 2019 Category: Urology & Nephrology Authors: van Raaij SE, Rennings AJ, Biemond BJ, Schols SE, Wiegerinck ET, Roelofs HM, Hoorn EJ, Walsh SB, Nijenhuis T, Swinkels DW, Van Swelm R Tags: Am J Physiol Renal Physiol Source Type: research