Drug Discovery For Nervous System Disorders (R01 Clinical Trials Not Allowed)

Funding Opportunity PAR-19-147 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports the discovery of novel compounds for the prevention and treatment of nervous system disorders. Through this FOA NIMH and NIA wish to stimulate research in: 1) Identification, design, synthesis, and preclinical testing of compounds of candidate therapeutics; 2) Initial hit-to-lead chemistry to improve activity of compounds against the target of interest; 3) Later stage lead optimization to improve efficacy and pharmacokinetics; and 4) Initial drug metabolism and pharmacokinetic (DMPK). Emphasis will be placed on projects that provide novel approaches for identifying potential therapeutic agents.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding