Using Lithium in Older Age Bipolar Disorder: Special Considerations

This study found lithium to be effective in late-life mania and hypomania. Th e remaining literature examining lithium in OABD was reviewed, comprising of a number of small open-label and retrospective studies, with special considerations highlighted. In summary, there is a small yet increasing geriatric evidence base that lithium is effective in OABD. Although there can be a dverse effects with lithium, it is generally well tolerated, and there are methods to minimize these risks. Further research would strengthen the evidence base for lithium therapy in OABD. In the meantime, lithium remains the gold-standard treatment for OABD.

http://link.springer.com/10.1007/s40266-018-0628-1

Source: Drugs and Aging - January 7, 2019 Category: Geriatrics Source Type: research