HMGB1 signaling blocking protects against carbapenem-resistant klebsiella pneumoniae in a murine model of infection.

CONCLUSION: These results indicate that HMGB1 may be an important contributor in these changes of CRKP-induced pneumonia. Thus, HMGB1 may provide a therapeutic target for reducing bacterial infection and lung inflammation in CRKP pneumonia. PMID: 30595050 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30595050?dopt=Abstract

Source: Experimental Lung Research - January 1, 2019 Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research

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