The “Toenail Sign” in MELAS May Be the End Stage of a Stroke-like Lesion

I read with interest the article by Kuwabara et  al. about an 11-year-old boy with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) due to the variant m.3243A>G who presented with gyral necrosis and cerebral atrophy on cerebral magnetic resonance imaging (MRI) compared with images three years earlier.1
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Correspondence Source Type: research