Multi-centre point-prevalence survey of hospital-acquired infections in Ghana

ConclusionA low HAI burden was found compared with findings from other low- and middle-income countries.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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AbstractRecent studies show that rectal colonization with low-level ciprofloxacin-resistantEscherichia coli (ciprofloxacin minimal inhibitory concentration (MIC) above the epidemiological cutoff point, but below the clinical breakpoint for resistance), i.e., in the range>  0.06–0.5 mg/L is an independent risk factor for febrile urinary tract infection after transrectal ultrasound-guided biopsy (TRUS-B) of the prostate, adding to the other risk posed by established ciprofloxacin resistance inE. coli (MIC  >  0.5 mg/L) as currently defined. We aimed to identify the quinolone that by...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Conclusion: The present study has shown the production of various virulent factors and developing drug resistance in UPEC. Treatment outcomes of patients harboring strains with no virulence factors seem to be better than the ones which contain multiple virulence factors. UPEC occurs because of multiple virulence factors. Biofilm formation and MRHA are more likely to be seen in catheterized patients. The drug resistance among UPEC is on rise; therefore, the selection of appropriate antibiotics (after antibiotic susceptibility testing) is must for proper treatment of patients and to avoid emergence of drug resistance. Signif...
Source: Annals of African Medicine - Category: African Health Authors: Source Type: research
Abstract The purpose of this research is to compare and enhance the antimicrobial and antibiofilm potentials of the biogenic selenium nanoparticles (Se NPs) produced by cost-effective and eco-friendly green methods. The synthesis of Se NPs is described in this manuscript by two different methods: a biogenic process using Penicillium chrysogenum filtrate and by utilizing gentamicin drug (CN) following the application of gamma irradiation. Se NPs were characterized by UV-Vis., HRTM, FTIR, XRD, DLS, SEM, and EDX mapping technique. Antimicrobial and antibiofilm activities of the synthesized Se NPs were investigated ag...
Source: Biological Trace Element Research - Category: Biology Authors: Tags: Biol Trace Elem Res Source Type: research
Microbial Drug Resistance, Ahead of Print.
Source: Microbial Drug Resistance - Category: Microbiology Authors: Source Type: research
Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Ting Huang, Jingjing Yang, Wanqing Zhou, Xinli Liu, Yongchun Pan, Yujun SongAbstractRapid and accurate detection of bacteria in urine is the key to improving the diagnostic efficiency of urinary tract infections. In this work, a microfluidic device was developed for visually quantifying pathogenic bacteria in urine without any external equipment. This pioneering strategy has high sensitivity, selectivity and accuracy for rapid detection of Escherichia coli and Staphylococcus aureus simultaneously. It not only shortens the entir...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Ovarian torsion is a rare cause of acute abdomen. It is very uncommon in the pediatric age group with an incidence of 2.7% of all children with acute pain abdomen [1]. Diagnosis in children is extremely difficult due to the overlapping presentation of commoner diseases i.e. gastroenteritis, urinary tract infection, appendicitis and intestinal obstruction
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: IMAGES IN Gynecological Surgery Source Type: research
Ovarian torsion is a rare cause of acute abdomen. It is very uncommon in the pediatric age group, with an incidence of 2.7% of all children with acute pain abdomen [1]. Diagnosis in children is extremely difficult because of the overlapping presentation of commoner diseases (i.e., gastroenteritis, urinary tract infection, appendicitis, and intestinal obstruction).
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Images in Gynecologic Surgery Source Type: research
CONCLUSION: The higher rate of infectious complications with CR and ESBL-positive strains suggests that the agents used for antibiotic prophylaxis should be reevaluated. It is important to consider local resistance data when using extended-spectrum agents to treat patients presenting with post-biopsy infectious complications. PMID: 31364100 [PubMed - as supplied by publisher]
Source: Urology Journal - Category: Urology & Nephrology Authors: Tags: Urol J Source Type: research
is one of the most common infections to affect humans. Uncomplicated infections most commonly occur in otherwise healthy women when uropathogenic bacteria, usually Escherichia coli, enter the bladder and overcome host innate immunity. Complicated infections occur in patients with an anatomical or functional abnormality of the urinary tract. Diagnosis is made on the basis of symptoms, and diagnostic precision is improved by urinalysis. Urine culture is important in patients with severe, recurrent or complicated infection and when diagnosis is uncertain, for example in children and elderly people.
Source: Medicine - Category: Internal Medicine Authors: Tags: Obstruction and infection Source Type: research
Third-generation cephalosporin resistance among Enterobacteriaceae, mediated by the spread of extended-spectrum β-lactamases (ESBLs), is a very serious medical concern with limited therapeutic options. Enmetazobactam (formerly AAI101) is a novel penicillanic sulfone β-lactamase inhibitor active against a wide range of ESBLs. The combination of enmetazobactam and cefepime has entered phase 3 development in patients with complicated urinary tract infections. Using the Clinical and Laboratory Standards Institute (CLSI) M23 tier 2 study design, broth microdilution MIC and disk diffusion quality control (QC) ranges we...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Bacteriology Source Type: research
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