Novel role of SF1 in alleviating thyroid-associated ophthalmopathy through the AMPK/mTOR signaling pathway.

CONCLUSION: Our result showed up-regulated SF1 may relieve TAO through suppressing cell proliferation and differentiation, but accelerating cell apoptosis by inhibiting the activation of the AMPK/mTOR signaling pathway.
PMID: 30562606 [PubMed - as supplied by publisher]

Source: Gene - December 15, 2018 Category: Genetics & Stem Cells Authors: Wang XX, Wang XX, Jia XF, Guo T, Xian TZ, Liu L, Xu ZJ, Guo Y, Deng X, Zhang LN, Man FL, Zhang XB, Chen T, Pan Q, Guo LX Tags: Gene Source Type: research